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Abstract Background Colorectal cancer is a leading cause of cancer mortality. Screening can be effective but is underutilized. System- or multi-level interventions could be effective at increasing screening, but most have been implemented and evaluated in higher-resource settings such as health maintenance organizations.
Given the disparities evident for colorectal cancer and the potential for screening to improve outcomes, there is a need to expand this work to include diverse settings, including those who treat economically disadvantaged patients. This trial was designed and is being implemented using a community-based participatory approach.
We will recruit 16 community health centers to this trial. This systems-level intervention consists of a menu of evidence-based implementation strategies for increasing colorectal cancer screening.
Health centers in the intervention arm then collaborate with the study team to tailor strategies to their own setting in order to maximize fit and acceptability.
Data are collected at the organizational level through interviews, and at the provider and patient levels through surveys. Patients complete a survey about their healthcare and screening utilization at baseline, six months, and twelve months.
Outcomes The primary outcome is colorectal cancer screening by patient self-report, supplemented by a chart-audit in a subsample of patients. Discussion Our study is A proposal for cancer intervention of the first to integrate community participatory strategies to a randomized controlled trial in a healthcare setting.
The multi-level approach will support the ability of the intervention to affect screening through multiple avenues.
The participatory approach will strengthen the chance that implementation strategies will be maintained after study completion and, supports external validity by increasing health center interest and willingness to participate. Colon cancer, Healthcare disparities, Screening, Randomized controlled trial, Intervention studies, Multi-level intervention, Implementation strategy, Community-based participatory research Background Colorectal cancer CRC is a leading cause of cancer death among men and women in the United States [ 1 ].
Many CRC deaths could be avoided through prevention and early detection activities; early stage CRC is associated with excellent survival [ 1 ]. CRC is unique among cancers, because screening is associated not only with early detection, but with prevention [ 4 ].
Cancers can be averted through the identification and removal of precancerous polyps. This rate is lower than many other cancer screenings. There are disparities in screening and survival from CRC.
|Breast Cancer Awareness | CC&GW | Sample Grant Proposal | Grant Writing Resource||The American Cancer Society first began conducting long-term prospective studies also called follow-up studies in the s. For these studies, large groups of individuals were recruited through a successful partnership between American Cancer Society researchers and volunteers.|
|NIH Guide: CANCER INTERVENTION AND SURVEILLANCE MODELING NETWORK (CISNET)||July 9, RFA: October 9, Application Receipt Date:|
|Bulling: Prevention and Intervention Proposal Research||
Uninsured patients fare worse than their insured counterparts even when adjusting for stage at diagnosis [ 7 - 12 ].
Given that CRC is a leading cancer diagnosis and disparately experienced, and that effective prevention and early detection tools reduce mortality by one-half but are under-utilized in routine primary care settings [ 1314 ], it is important to investigate the feasibility and effectiveness of strategies to increase screening.
Interventions to increase CRC rates that are focused on individual level factors have had only minimal to moderate success in getting patients screened. While individual-level strategies can be effective and have promise, systems- or multi-level approaches have the potential to reach a wider swath of the patient population and thus may have more overall impact [ 15 - 18 ].
Such approaches can set the stage to increase the likelihood of patient-provider discussion about CRC screening as well as increase the likelihood that screening is referred and completed.
Most interventions have been tested in structured and well-resourced settings [ 19 - 22 ]. Our objective in this study is to conduct a practical clinical trial [ 23 - 27 ] to evaluate the viability and effectiveness of evidence-based implementation strategies in community health centers serving populations disparately affected by CRC.
To achieve our stated aims, we are developing, implementing, and evaluating a systems-level intervention aimed at increasing CRC screening. The long-term goal is to reduce CRC disparities by developing sustainable and disseminable implementation approaches that will effectively promote informed decisions about CRC screening across a variety of settings, particularly those considered underserved.
Our protocol is described below. Using a rolling recruitment, community health centers CHCs are randomized to either intervention or comparison i.NCI’s prevention research has a broad focus, from identifying environmental and lifestyle factors that influence cancer risk to studying the biology of how cancer develops and studying ways to disseminate prevention interventions.
Breast Cancer Awareness This successful proposal was prepared by working closely with staff of the grantee. A slightly modified version was funded by Marin Community Foundation for $25, Cancer Prevention and Control: Skin Cancer Prevention Skin cancer prevention interventions in primary school settings encourage children in kindergarten through eighth (CDC) resources on skin cancer prevention at benjaminpohle.com gov/cancer/skin to find publications, manuals, toolkits.
Jul 09, · CANCER INTERVENTION AND SURVEILLANCE MODELING NETWORK (CISNET) Release surveillance research questions which this application is designed to address and the importance of these issues for cancer control in the US.
If the proposal includes the modeling of trends outside of the US, justification must be given as to what special. Women with breast cancer can make use of Complementary/ Alternative Medicine (CAM) in treating this disease.
They do not have risks, and the cost is relatively low. CAM is medical intervention that includes a number of treatment methods like chiropractic, acupuncture, and massage therapy.
This research proposal sample shouldn’t be. Call for Proposals: Preventing deaths from cervical cancer Unitaid is pleased to announce a new Call for Proposals for the area for intervention: Optimizing management of coinfections and comorbidities in people living with HIV.